The aim of toxicologic pathology

20 Nov

The aim of toxicologic pathology

  Health

Toxicologic pathology is a branch of chemical sciences that aims to ascertain that people experience as few ill effects as possible when using certain chemical and medicinal products. How is this done? By carrying out thorough research on non-human subjects to see what the effects are and establishing limiting values below which the health risks of using a certain substance is negligible or non-existent.  The emphasis of toxicologic pathology lies in the identification of relevant pathological changes and interpreting how the results from animal testing will apply to humans. This risk assessment, such as the one carried out by Global Pathology Support, will determine whether the product, such as a vaccine , is considered safe for distribution.

Why toxicologic pathology is important

Testing chemical products and medicines, as carried out by Global Pathology Support, for adverse side effects seems evident. However, in the past this was not always the case, which led to various disasters. For example, proper toxicologic pathology testing would have shown DDT and other types of pesticide to be carcinogenic and thus dangerous to humans when they enter the human diet even at low levels. The same applies to the carcinogenic effects of synthetic estrogen diethylstilbestrol in utero and the teratogenic effects of Thalidomide which caused many children with birth defects to be born in the sixties.

Do you want toxicologic pathology testing for your chemical substances?

Is your company developing chemical substances or products meant for human consumption? Contact Global Pathology Support to carry out toxicologic pathology testing to determine the possible side effects. The combine will dose rodent and non-rodent species with a new products for up to one month. This process helps reveal up to 90% of adverse effects. Of course, the experienced pathologist is needed to interpret the result to avoid over- and underprediction. That requires through education, continuous training and a National Board Certification from a recognized institution. All of which you will find at Global Pathology Support.

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